Differences in the rates of cellular division and differences in the amount of time spent in each stage of cellular division are important differentiators between healthy cells and cancer cells (Sherr 1996, Visconti 2016).  Likewise, cancer cells often form erroneous mitotic structures during cellular division and these erroneous structures can contribute to further disease progression (Milunović-Jevtić 2016, Bakhoum 2018). As such, the study of cellular division and and its machinery has led to the development of numerous anti-cancer drugs (Florian 2016, Steinmetz 2018).

Content

Dataset of Jurkat cells from https://github.com/theislab/deepflow (Eulenberg 2017).

Eulenberg P, Köhler N, et al. Reconstructing cell cycle and disease progression using deep learning. Nature Communications. 2017. Vol 8(1): p463. https://www.ncbi.nlm.nih.gov/pubmed/28878212.

Complimentary dataset of Nematode cells acquired independently using a FoldScope microscope.

Acknowledgements

Photo by Jaron Nix on Unsplash

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