# About This selection of images are controls selected from a screen to find novel anti-infectives using the roundworm C.elegans . The animals were exposed to the pathogen Enterococcus faecalis and either untreated or treated with ampicillin, a known antibiotic against the pathogen. The untreated (negative control) worms display predominantly the "dead" phenotype: worms appear rod-like in shape and slightly uneven in texture. The treated (ampicillin, positive control) worms display predominantly the "live" phenotype: worms appear curved in shape and smooth in texture. For more information, please see Moy et al. (ACS Chem Biol, 2009) [http://dx.doi.org/10.1021/cb900084v] # Images One image per channel (Channel 1 = brightfield; channel 2 = GFP) was acquired at MGH on a Discovery-1 automated microscope (Molecular Devices). Original image size is 696 x 520 pixels. Images are available in 16-bit TIF. # Ground Truth The 384 images are from a plate of positive and negative controls. The images are named using this format: